Decreased Cerebrospinal Fluid Flow is Associated with Cognitive Decline

Many neurodegenerative conditions are associated with the accumulation of forms of metabolic waste in the central nervous system, protein aggregates that form solid deposits between or within cells. Tauopathies such as frontotemporal dementia are associated with tau aggregates, synucleinopathies such as Parkinson’s disease with α-synuclein, and amyloidoses with varying forms of amyloid, such as the amyloid-β found in elevated amounts in Alzheimer’s disease patients. Alzheimer’s itself is an amyloidosis that also becomes a tauopathy in its later stages. These protein aggregates and their surrounding halos of harmful biochemistry disrupt normal brain function and, in the worse cases, kill neurons. Eventually they kill the patient. With the exception of certain inherited conditions, in which cellular biochemistry is broken due to an unfortunate and unlucky mutation, why

from https://www.fightaging.org/archives/2019/05/decreased-cerebrospinal-fluid-flow-is-associated-with-cognitive-decline/

from
https://healthnews010.tumblr.com/post/185217491928

From https://johnher1.blogspot.com/2019/05/decreased-cerebrospinal-fluid-flow-is.html

Author: John Her

Juice is a drink made from the extraction or pressing of the natural liquid contained in fruit and vegetables. It can also refer to liquids that are flavored with concentrate or other biological food sources, such as meat or seafood, such as clam juice.

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